Endocrine Abstracts

Hyperandrogenemia (elevated testosterone, T) and metabolic dysfunction are hallmarks of polycystic ovary syndrome (PCOS), which can have varying degrees of ovulatory dysfunction. Adipocyte hypertrophy, induced by obesity and hyperandrogenemia, has been suggested to contribute to the systemic low-grade inflammation thought to be one of the drivers leading to reproductive dysfunction in women with PCOS. However, whether hyperandrogenemia and adipocyte hypertrophy per se induce a...